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Implement in-house state-of-the-art motion-tracking methods into our novel PAI application and evaluate its performance. During a scan, motion artifacts arise as a result of movements of the operator or the patient, and from breathing and tissue movements. To reduce movements of the operator and patient we have developed a transducer holder and stabilized the patient using a vacuum pillow (Sheikh R et al.,  IEEE 2018, In press). To reduce artifacts from breathing and tissue movements we plan to utilize in-house 2D/3D motion estimation methods (Nilsson T et al.,  Proc IEEE Ultrason 2013; Albinsson J et al.,  Ultrasound Med Biol 2014; Albinsson J et al.,  Med Biol Eng Comput 2017) to obtain a full spectrum with high quality from each pixel in the image plane. Motion tracking


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